Isabella has had a successful career as a model with over 500 covers including Vogue, Elle and Vanity Fair, working with such renowned photographers as Richard Avedon and Bruce Weber. As an actress she has worked on numerous features in both Europe and the U.S.A., most notably, BLUE VELVET, BIG NIGHT and FEARLESS.
She has recently appeared in television programs including Napoleon, Merlin, and 30 Rock. Her first foray behind the camera was as the writer and creator of MY DAD IS 100 YEARS OLD, directed by Guy Maddin. This film was included in a retrospective of her father, Roberto Rossellini's amazing body of work which screened at MOMA and on an international Cinematheque tour in various venues around the world. She made her directorial debut in 2008 with GREEN PORNO.